Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056425 | 0.93 | USP2 (0.67) | USP2L3MBTL1SMN1; SMN2CYP2D6GAA | |
| SCHEMBL14116865 | 0.93 | USP2 (0.67) | USP2L3MBTL1SMN1; SMN2CYP2D6GAA | |
| Hydrochloric Acid SCHEMBL8577317 | 0.91 | USP2 (0.64) | USP2L3MBTL1SMN1; SMN2CYP2D6GAA | |
| SCHEMBL21301880 | 0.86 | USP2 (0.53) | USP2L3MBTL1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL20027940 | 0.84 | KMT2A (0.60) | L3MBTL1SMN1; SMN2CYP2D6POLBALDH1A1 | |
| SCHEMBL14116880 | 0.84 | KMT2A (0.60) | L3MBTL1SMN1; SMN2CYP2D6POLBALDH1A1 | |
| SCHEMBL14116870 | 0.84 | KMT2A (0.54) | L3MBTL1SMN1; SMN2CYP2D6POLBCYP2C19 | |
| SCHEMBL14355276 | 0.84 | KMT2A (0.54) | L3MBTL1SMN1; SMN2CYP2D6POLBCYP2C19 | |
| SCHEMBL67311 | 0.84 | KMT2A (0.60) | L3MBTL1SMN1; SMN2CYP2D6POLBALDH1A1 | |
| SCHEMBL68147 | 0.82 | KMT2A (0.64) | L3MBTL1SMN1; SMN2CYP2D6POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063764-A2 | FUSED PYRROLOCARBAZOLES AND METHODS FOR THE PREPARATION THEREOF | CEPHALON, INC. (US) | 2005-07-14 | — | — | WO | disclosed |