Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283570 | 0.79 | TSHR (0.52) | ALDH1A1KMT2AGAAKDM4EMEN1 | |
| SCHEMBL8284340 | 0.78 | TDP1 (0.36) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL315248 | 0.75 | MGLL (0.57) | KMT2AGAAMEN1MAPT | |
| SCHEMBL314394 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2AGAAKDM4E | |
| SCHEMBL315255 | 0.72 | MEN1 (0.58) | KMT2AMEN1 | |
| SCHEMBL8284357 | 0.71 | KMT2A (0.57) | KMT2A | |
| SCHEMBL18330505 | 0.61 | ALDH1A1 (0.50) | ALDH1A1KMT2AGAAMEN1MAPT | |
| SCHEMBL18330407 | 0.58 | TSHR (0.51) | ALDH1A1LMNAKMT2AGAAKDM4E | |
| SCHEMBL14204880 | 0.58 | KDM4E (0.51) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL13149373 | 0.57 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063754-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-07-14 | — | — | WO | disclosed |