Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2541975 | 0.83 | TNF (0.43) | SLC22A12DAOADORA2AADORA1PIK3C2B | |
| SCHEMBL14271694 | 0.77 | HSP90AA1 (0.39) | SLC22A12DAOADORA2AADORA1ALDH1A1 | |
| SCHEMBL2539136 | 0.73 | SLC22A12 (0.43) | SLC22A12DAOADORA2AADORA1PIK3C2B | |
| SCHEMBL8285540 | 0.69 | TRPC5 (0.46) | PIK3C2BKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8283839 | 0.66 | TNF (0.40) | SLC22A12DAOADORA2AADORA1PIK3C2B | |
| SCHEMBL13773411 | 0.65 | CDK1 (0.45) | SLC22A12DAOADORA2AADORA1PIK3C2B | |
| SCHEMBL2542294 | 0.65 | RPS6KA5 (0.41) | SLC22A12DAOADORA2AADORA1PIK3C2B | |
| SCHEMBL4990218 | 0.64 | KDM4E (0.54) | DAOKMT2AALDH1A1HTTHDAC6 | |
| SCHEMBL29856020 | 0.64 | KDM4E (0.54) | DAOKMT2AALDH1A1HTTHDAC6 | |
| SCHEMBL6168555 | 0.62 | GALR3 (0.52) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |