Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054416 | 0.85 | ALDH1A1 (0.52) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL8284664 | 0.84 | LMNA (0.55) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL1120600 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL14442101 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL1120598 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL3427721 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL12402078 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL1120601 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL6321567 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL13476162 | 0.82 | LMNA (0.82) | LMNATP53ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097140-A2 | SELECTIVE ANTAGONISTS OF A2A ADENOSINE RECEPTORS | ADENOSINE THERAPEUTICS, LLC (US) | 2005-10-20 | — | — | WO | disclosed |