Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7899272 | 0.98 | TSHR (0.52) | TSHRALDH1A1AOC3MAPK1CARM1 | |
| SCHEMBL10660626 | 0.80 | TSHR (0.54) | TSHRALDH1A1AOC3MAPK1CARM1 | |
| SCHEMBL28827127 | 0.79 | NPC1 (0.43) | ALDH1A1AOC3MAPK1NPC1RAB9A | |
| SCHEMBL112375 | 0.78 | TSHR (0.58) | TSHRALDH1A1AOC3MAPK1CARM1 | |
| SCHEMBL5498059 | 0.78 | TSHR (0.46) | TSHRALDH1A1AOC3MAPK1CARM1 | |
| SCHEMBL3921323 | 0.76 | CA2 (0.43) | TSHRALDH1A1CYP2C19LMNACNR2 | |
| SCHEMBL9545622 | 0.76 | TSHR (0.50) | TSHRALDH1A1AOC3MAPK1CARM1 | |
| Hydrochloric Acid SCHEMBL31556140 | 0.76 | TSHR (0.56) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL828470 | 0.76 | TAAR1 (0.58) | AOC3SLC6A2SLC6A4ADRA1ASLC6A3 | |
| SCHEMBL6621098 | 0.76 | TSHR (0.50) | TSHRALDH1A1AOC3MAPK1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543236-B1 | METHOD FOR PREPARING AVIBACTAM INTERMEDIATE | XINFA PHARMACEUTICAL CO LTD (CN) | 2022-02-16 | — | — | EP | claimed |
| CN-107827817-B | Method for synthesizing formamide derivative through molybdenum catalytic formylation reaction | 湘潭大学 | 2020-03-13 | — | — | CN | claimed |
| US-10570132-B2 | Process for preparing an intermediate for avibactam | XINFA PHARMACEUTICAL CO., LTD (CN) | 2020-02-25 | — | — | US | claimed |
| EP-3543236-A1 | METHOD FOR PREPARING AVIBACTAM INTERMEDIATE | Xinfa Pharmaceutical Co., Ltd (CN) | 2019-09-25 | — | — | EP | claimed |
| US-20190263812-A1 | PROCESS FOR PREPARING AN INTERMEDIATE FOR AVIBACTAM | XINFA PHARMACEUTICAL CO., LTD (CN) | 2019-08-29 | — | — | US | claimed |
| CN-103709161-B | One-dimensional organic semiconductor nanowire with fluorescence and photoconduction dual response for organic amine gas as well as preparation method and application of nanowire | CHINESE ACAD INST CHEMISTRY | 2015-05-20 | — | — | CN | claimed |
| CN-103709161-A | One-dimensional organic semiconductor nanowire with fluorescence and photoconduction dual response for organic amine gas as well as preparation method and application of nanowire | CHINESE ACAD INST CHEMISTRY | 2014-04-09 | — | — | CN | claimed |
| WO-2012033956-A1 | COGNITION ENHANCING COMPOUNDS AND COMPOSITIONS, METHODS OF MAKING, AND METHODS OF TREATING | MITHRIDION, INC. (US) | 2012-03-15 | — | — | WO | claimed |
| EP-1511730-B8 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2009-04-08 | — | — | EP | claimed |
| US-20060128734-A1 | Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases | FLOERSHEIMER ANDREAS | 2006-06-15 | — | — | US | claimed |
| CN-1656073-A | Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2005-08-17 | — | — | CN | claimed |
| EP-1511730-A2 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | Novartis AG (CH) | 2005-03-09 | — | — | EP | claimed |
| WO-2003099771-A2 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2003-12-04 | — | — | WO | claimed |
| EP-1155001-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2003-05-28 | — | — | EP | claimed |
| EP-1155001-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| JP-6025163-A | — | — | None | — | — | JP | disclosed |
| EP-4731689-A1 | METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE | Covestro Deutschland AG (DE) | 2026-04-29 | — | — | EP | disclosed |
| US-4089956-A | 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof | SMITHKLINE CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570132-B2 | Process for preparing an intermediate for avibactam | ODC1, UROD, STS | TSHR 2379/4885ALDH1A1 2869/4885AOC3 115/4885 |
| US-20190263812-A1 | PROCESS FOR PREPARING AN INTERMEDIATE FOR AVIBACTAM | ODC1, UROD, STS | TSHR 2379/4885ALDH1A1 2869/4885AOC3 115/4885 |
| US-20060128734-A1 | Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases | UCK2, PRKDC, PRKACA | TSHR 3952/4885ALDH1A1 3040/4885AOC3 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.