Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284011 | 0.87 | MTNR1A (0.68) | MTNR1BMTNR1AKMT2AMEN1HPGD | |
| SCHEMBL6874085 | 0.87 | NQO2 (0.51) | MTNR1BMTNR1AKMT2AMEN1ADRB2 | |
| SCHEMBL17846028 | 0.85 | MTNR1A (0.50) | MTNR1BMTNR1AKMT2AMEN1ADRB2 | |
| SCHEMBL8493187 | 0.84 | MTNR1A (0.52) | MTNR1BMTNR1A | |
| SCHEMBL8504979 | 0.84 | MTNR1A (0.55) | MTNR1BMTNR1AKMT2AMEN1ADRB2 | |
| SCHEMBL8284003 | 0.83 | MTNR1A (0.48) | MTNR1BMTNR1AKMT2AMEN1ADRB2 | |
| SCHEMBL7645845 | 0.80 | HRH1 (0.54) | MTNR1BMTNR1AKDM4EALDH1A1 | |
| SCHEMBL8286476 | 0.80 | KMT2A (0.52) | MTNR1BMTNR1AKMT2ACNR1HPGD | |
| SCHEMBL6871966 | 0.79 | TDP1 (0.49) | ADRB2ADRB1 | |
| SCHEMBL8285817 | 0.78 | PPARD (0.46) | MTNR1BMTNR1APPARDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |