Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.64 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 5/20 | 0.51 |
| ▸ | CTSH | P09668 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991650 | 0.83 | CTSK (0.60) | CTSKCTSLCTSBCTSH | |
| SCHEMBL5674723 | 0.79 | CTSK (0.53) | CTSKCTSLCTSBCTSH | |
| SCHEMBL418758 | 0.77 | CTSK (0.63) | CTSK | |
| SCHEMBL12635080 | 0.77 | CTSK (0.63) | CTSK | |
| SCHEMBL3667036 | 0.77 | CTSK (0.63) | CTSK | |
| SCHEMBL15715052 | 0.77 | ALOX15 (0.47) | CTSKALOX15 | |
| SCHEMBL13245698 | 0.77 | CTSK (0.49) | CTSKCTSLCTSBCTSH | |
| SCHEMBL15757825 | 0.76 | CTSK (0.61) | CTSKCTSLCTSBCTSH | |
| SCHEMBL328961 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL56438 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368878-A1 | Peptidomimetic protease inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2005058821-A1 | INHIBITORS OF HEPATITIS C VIRUS NS3/NS4A SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-06-30 | — | — | WO | disclosed |