Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34474623 | 0.83 | PREP (0.47) | PREPLMNATSHRL3MBTL1KDM4E | |
| SCHEMBL30511005 | 0.83 | PREP (0.47) | PREPLMNATSHRL3MBTL1KDM4E | |
| SCHEMBL5566433 | 0.81 | ITGB1 (0.43) | PARP1POLB | |
| SCHEMBL30416618 | 0.77 | KLK7 (0.48) | PREPACE2KLK7PARP1 | |
| SCHEMBL27286074 | 0.76 | POLB (0.52) | LMNATSHRL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL30946916 | 0.76 | POLB (0.52) | LMNATSHRL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL30317557 | 0.76 | SIGMAR1 (0.45) | PREPLMNATSHRL3MBTL1KDM4E | |
| SCHEMBL25762497 | 0.75 | PREP (0.42) | PREPLMNATSHRL3MBTL1KDM4E | |
| SCHEMBL10060303 | 0.75 | KLK7 (0.46) | PREPACE2KLK7PARP1 | |
| SCHEMBL30511055 | 0.74 | SIGMAR1 (0.50) | KLK7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090329-A9 | NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF | JERINI AG (DE) | 2007-02-01 | — | — | WO | disclosed |