Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511055 | 0.97 | SIGMAR1 (0.50) | KLK7SIGMAR1PARP1MEN1KMT2A | |
| SCHEMBL30511005 | 0.92 | PREP (0.47) | KLK7SIGMAR1PARP1PREPHTR2C | |
| SCHEMBL34474623 | 0.92 | PREP (0.47) | KLK7SIGMAR1PARP1PREPHTR2C | |
| SCHEMBL30511053 | 0.90 | KLK7 (0.47) | KLK7SIGMAR1PARP1MEN1KMT2A | |
| SCHEMBL30511049 | 0.90 | KLK7 (0.47) | KLK7SIGMAR1PARP1MEN1KMT2A | |
| SCHEMBL30393200 | 0.87 | SIGMAR1 (0.48) | KLK7SIGMAR1PARP1MEN1KMT2A | |
| SCHEMBL10060303 | 0.87 | KLK7 (0.46) | KLK7SIGMAR1PARP1MEN1KMT2A | |
| SCHEMBL25184580 | 0.87 | SIGMAR1 (0.51) | SIGMAR1FKBP1APREPACE2BCHE | |
| SCHEMBL25180646 | 0.87 | SIGMAR1 (0.51) | SIGMAR1FKBP1APREPACE2BCHE | |
| SCHEMBL25416510 | 0.84 | SIGMAR1 (0.56) | SIGMAR1MEN1KMT2AFKBP1ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034200-A1 | Prodrugs of Neurosteroid Analogs and Uses Thereof | UNIV EMORY (US) | 2025-01-30 | — | — | US | disclosed |
| US-20250026781-A1 | Prodrugs of Neurosteroid Analogs and Uses Thereof | UNIV EMORY (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2024197317-A2 | NEUROSTEROIDS AND PRODRUGS THEREOF | EMORY UNIVERSITY (US) | 2024-09-26 | — | — | WO | disclosed |
| WO-2023086432-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086438-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034200-A1 | Prodrugs of Neurosteroid Analogs and Uses Thereof | CYP11B2, CYP11B1, CYP21A2 | KLK7 1237/4885SIGMAR1 2792/4885PARP1 1816/4885 |
| US-20250026781-A1 | Prodrugs of Neurosteroid Analogs and Uses Thereof | CYP11B1, CYP11B2, CYP11A1 | KLK7 2345/4885SIGMAR1 2309/4885PARP1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.