Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289546 | 0.98 | ESR2 (1.00) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3279191 | 0.88 | ESR2 (1.00) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6247335 | 0.82 | ALDH1A1 (0.71) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6246194 | 0.82 | MEN1 (0.76) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5805290 | 0.81 | ALDH1A1 (0.70) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5805289 | 0.81 | ALDH1A1 (0.70) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6246144 | 0.81 | MEN1 (0.83) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6203556 | 0.80 | ALDH1A1 (0.73) | ESR2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5804321 | 0.80 | ALDH1A1 (0.76) | ESR2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5804325 | 0.80 | ALDH1A1 (0.76) | ESR2POLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |