Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 15/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13837632 | 0.87 | PRKCZ (1.00) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL689204 | 0.82 | PRKCZ (1.00) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13837647 | 0.81 | PRKCZ (1.00) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31061179 | 0.81 | PRKCZ (1.00) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5919183 | 0.79 | PRKCZ (0.67) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8288641 | 0.79 | PRKCZ (0.75) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13837635 | 0.79 | PRKCZ (1.00) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8288644 | 0.78 | PRKCZ (0.77) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3976339 | 0.78 | PRKCZ (0.58) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8288639 | 0.78 | ALDH1A1 (0.76) | PRKCZALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |