Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | FLT3 | P36888 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289712 | 0.97 | KDM4E (0.67) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL4390871 | 0.89 | MAPT (0.73) | MAPTLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL5455182 | 0.87 | MAPT (0.81) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL8289499 | 0.87 | ALDH1A1 (0.73) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL8289688 | 0.86 | ALDH1A1 (0.76) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL8289834 | 0.84 | KDM4E (0.70) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL5467546 | 0.83 | FLT3 (0.76) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL5453467 | 0.80 | FLT3 (1.00) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL5452975 | 0.80 | MAPT (1.00) | MAPTFLT3LMNAMEN1KMT2A | |
| SCHEMBL11485439 | 0.80 | PTPN1 (0.78) | MAPTFLT3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |