Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288594 | 0.80 | TP53 (0.59) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL8288570 | 0.79 | MAPT (0.59) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13831340 | 0.77 | NPC1 (0.69) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL21045433 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL17725688 | 0.75 | MEN1 (0.63) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL17725679 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL8289705 | 0.74 | ALDH1A1 (0.84) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL8289651 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL12349849 | 0.71 | MEN1 (0.61) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4215854 | 0.71 | ALDH1A1 (0.76) | ALDH1A1MAPTHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |