Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525660 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL10467196 | 0.72 | SMN1; SMN2 (0.66) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL14268239 | 0.70 | MAPT (0.60) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL27414138 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL7016372 | 0.67 | SCD (0.61) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL10591917 | 0.67 | RAB9A (0.76) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3093223 | 0.66 | SCD (0.49) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL20392523 | 0.66 | RAB9A (0.59) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL525018 | 0.66 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL27537297 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |