Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | KDM4A | O75164 | 2/20 | 0.57 |
| ▸ | KDM4B | O94953 | 2/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.57 |
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433339 | 0.88 | LMNA (0.73) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL14448967 | 0.83 | HDAC8 (0.65) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14448969 | 0.81 | MAPT (0.68) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4956701 | 0.81 | ADORA3 (0.74) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL14448968 | 0.79 | KDM1A (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6263121 | 0.79 | PI4KB (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4424123 | 0.77 | PLAU (0.54) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1270375 | 0.76 | SCD (0.89) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL31361475 | 0.76 | ADORA3 (0.81) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL5904009 | 0.76 | PTPN1 (0.57) | MEN1KMT2AKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | HDAC1, HDAC11, HDAC2 | MAPT 3965/4885LMNA 672/4885MEN1 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.