Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.73 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997928 | 0.87 | GRIN2C (0.67) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7003164 | 0.87 | FLT3 (0.70) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7002672 | 0.85 | FLT3 (1.00) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7902809 | 0.83 | GRIN2C (1.00) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7003277 | 0.82 | FLT3 (0.69) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL6999456 | 0.82 | GRIN2C (0.79) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL6998742 | 0.81 | FLT3 (0.83) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL6996786 | 0.79 | FLT3 (0.70) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7004549 | 0.78 | FLT3 (0.68) | FLT3GRIN2CRAB9ANPC1ALDH1A1 | |
| SCHEMBL7003132 | 0.77 | ALDH1A1 (0.64) | FLT3GRIN2CRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |