SCHEMBL8289010

SCHEMBL8289010

Cc1ccc(C2=NCCN2C)cn1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.38
F10 P00742 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7006039 0.81 CHRNB2 (0.48) F10
SCHEMBL14085132 0.81 TOP2A (0.44) F10
SCHEMBL8286902 0.78 PTAFR (0.46) F10
SCHEMBL5502730 0.73 TOP2A (0.36) F10
SCHEMBL7011069 0.72 CHRNB2 (0.46) F10
SCHEMBL122260 0.72 ADORA3 (0.46)
Water SCHEMBL9451270 0.71 PTAFR (0.43) F10
Water SCHEMBL9451273 0.71 PTAFR (0.43) F10
Hydrochloric Acid SCHEMBL6766285 0.71 TOP2A (0.41)
SCHEMBL23080997 0.70 PTAFR (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005032490-A2 CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-04-14 WO disclosed