Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 8/20 | 0.66 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.66 |
| ▸ | USP5 | P45974 | 1/20 | 0.66 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RGS12 | O14924 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349344 | 0.92 | USP9X (0.78) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL14402866 | 0.88 | USP9X (0.59) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL1315700 | 0.87 | USP9X (0.85) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL1315703 | 0.87 | USP9X (0.85) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL1315701 | 0.87 | USP9X (0.85) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL1315698 | 0.87 | USP9X (0.85) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL13474839 | 0.87 | USP9X (0.58) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL882591 | 0.83 | USP9X (0.49) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL882577 | 0.81 | USP9X (0.59) | USP9XUCHL1USP5STAT3ALDH1A1 | |
| SCHEMBL13474789 | 0.80 | STAT3 (0.53) | USP9XUCHL1USP5STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005954-A2 | TRYPHOSTIN-ANALOGS FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-01-10 | — | — | WO | disclosed |
| WO-2005058829-A1 | COMPOUNDS FOR TREATMENT OF CELL PROLIFERATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-06-30 | — | — | WO | disclosed |