Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP22 | Q9NRW4 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766490 | 0.76 | MAPT (0.55) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9917038 | 0.73 | DUSP22 (0.77) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10035996 | 0.73 | DUSP22 (0.77) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12123516 | 0.73 | DUSP22 (0.77) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3892527 | 0.71 | MEN1 (0.60) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3892524 | 0.71 | MEN1 (0.60) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10035969 | 0.70 | MEN1 (0.73) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11116026 | 0.70 | MAPT (0.60) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8337257 | 0.69 | KMT2A (0.49) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20005694 | 0.69 | MEN1 (0.62) | DUSP22MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |