Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766490 | 0.73 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL13855614 | 0.73 | CISD1 (0.44) | MAPTALDH1A1POLBRAB9ALMNA | |
| SCHEMBL3906427 | 0.71 | KMT2A (0.58) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL3906422 | 0.71 | KMT2A (0.58) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL8339399 | 0.70 | CISD1 (0.41) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL8289157 | 0.69 | DUSP22 (0.52) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL19419941 | 0.67 | KMT2A (0.77) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL13058066 | 0.67 | CISD1 (0.54) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL13081727 | 0.67 | PTPN12 (0.48) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL3895153 | 0.67 | MEN1 (0.54) | KMT2AMEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |