Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP22 | Q9NRW4 | 9/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035996 | 1.00 | DUSP22 (0.77) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL12123516 | 1.00 | DUSP22 (0.77) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL10035969 | 0.90 | MEN1 (0.73) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL6789390 | 0.87 | DUSP22 (1.00) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL10491520 | 0.86 | KMT2A (0.76) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL10491519 | 0.86 | KMT2A (0.76) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL24217824 | 0.84 | DUSP22 (1.00) | DUSP22KMT2AMEN1DUSP3 | |
| SCHEMBL2403963 | 0.83 | HSPD1 (0.81) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL2403957 | 0.83 | HSPD1 (0.81) | DUSP22KMT2AMEN1ALDH1A1DUSP3 | |
| SCHEMBL2403960 | 0.83 | HSPD1 (0.81) | DUSP22KMT2AMEN1ALDH1A1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160330960-A1 | Honeybee Repellents and Uses Thereof | INSCENT, INC. (US) | 2016-11-17 | — | — | US | disclosed |
| US-9439434-B2 | Honeybee repellents and uses thereof | INSCENT, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160250194-A1 | Methods of Making and Using Thioxothiazolidine and Rhodanine Derivatives as HIV-1 and JSP-1 Inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-09-01 | — | — | US | disclosed |
| US-20140155261-A1 | Honeybee Repellents and Uses Thereof | INSCENT, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20130253021-A1 | Methods of Making and Using Thioxothiazolidine and Rhodanine Derivatives as HIV-1 and JSP-1 Inhibitors | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2013142831-A1 | METHODS OF MAKING AND USING THIOXOTHIAZOLIDINE AND RHODANINE DERIVATIVES AS HIV-1 AND JSP-1 INHIBITORS | SOUTHERN METHODIST UNIVERSITY (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20120149710-A1 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-06-14 | — | — | US | disclosed |
| US-7235573-B2 | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160330960-A1 | Honeybee Repellents and Uses Thereof | ACHE, AHNAK, L3MBTL3 | DUSP22 2186/4885KMT2A 794/4885MEN1 2382/4885 |
| US-20120149710-A1 | SORTASE A INHIBITORS | STS, ENGASE, SPR | DUSP22 4056/4885KMT2A 3208/4885MEN1 3994/4885 |
| US-20130253021-A1 | Methods of Making and Using Thioxothiazolidine and Rhodanine Derivatives as HIV-1 and JSP-1 Inhibitors | TPMT, TASP1, RAET1L | DUSP22 1548/4885KMT2A 2690/4885MEN1 3728/4885 |
| US-20160250194-A1 | Methods of Making and Using Thioxothiazolidine and Rhodanine Derivatives as HIV-1 and JSP-1 Inhibitors | TPMT, TASP1, RAET1L | DUSP22 1548/4885KMT2A 2690/4885MEN1 3728/4885 |
| US-20140155261-A1 | Honeybee Repellents and Uses Thereof | ACHE, AHNAK, L3MBTL3 | DUSP22 2186/4885KMT2A 794/4885MEN1 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.