⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828 | 0.83 | HRH3 (0.79) | — | |
| Hydrochloric Acid SCHEMBL3162690 | 0.79 | HRH3 (0.73) | — | |
| Iodide SCHEMBL29191162 | 0.79 | HRH3 (0.73) | — | |
| Bromide SCHEMBL29198706 | 0.79 | HRH3 (0.73) | — | |
| Iodide SCHEMBL28395414 | 0.79 | HRH3 (0.73) | — | |
| Hydrochloric Acid SCHEMBL3168189 | 0.79 | HRH3 (0.73) | — | |
| SCHEMBL8251234 | 0.77 | TAAR1 (0.56) | — | |
| Benzene SCHEMBL734439 | 0.76 | LOXL2 (0.80) | — | |
| SCHEMBL6314683 | 0.73 | HRH3 (0.65) | — | |
| Methyl Alcohol SCHEMBL22528993 | 0.73 | ABAT (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807644-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807644-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230002403-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-01-05 | — | — | US | disclosed |
| WO-2021231474-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| CN-106146567-B | Organometallic compound and organic electroluminescent device comprising the same | 财团法人工业技术研究院 | 2019-10-01 | — | — | CN | disclosed |
| CN-110072981-A | Automobile gear lubricant oil composite | 三井化学株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-107624112-A | Small molecule inhibitors of lactate dehydrogenase and methods of use thereof | 美国政府健康及人类服务部 | 2018-01-23 | — | — | CN | disclosed |
| CN-106795449-A | Lubricant oil composite | 三井化学株式会社 | 2017-05-31 | — | — | CN | disclosed |
| US-9573942-B2 | HIV inhibiting 5-amido substituted pyrimidines | JANSSEN SCIENCES IRELAND UC (IE) | 2017-02-21 | — | — | US | disclosed |
| CN-106133006-A | Ethylene/alpha olefin polymer and lubricating oil | 三井化学株式会社 | 2016-11-16 | — | — | CN | disclosed |
| US-20090309070-A1 | COMPOSITIONS FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-12-17 | — | — | US | disclosed |
| WO-2009052078-A1 | CCR10 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| US-20090033208-A1 | FILM FORMING COMPOSITION AND ORGANIC ELECTROLUMINESCENT DEVICE | PIONEER CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2006-08-10 | — | — | US | disclosed |
| WO-2005058298-A2 | FK228 ANALOGS AND THEIR USE AS HDAC-INHIBITORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-06-30 | — | — | WO | disclosed |
| CN-1204126-C | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2005-06-01 | — | — | CN | disclosed |
| CN-1334805-A | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2002-02-06 | — | — | CN | disclosed |
| CN-1208050-A | Olefin thermoplastic elastomer composition | MITSUI CHEMICALS INC (JP) | 1999-02-17 | — | — | CN | disclosed |
| EP-0199260-A2 | Boronic acid adducts of technetium-99M dioxime complexes | E.R. Squibb & Sons, Inc. (US) | 1986-10-29 | — | — | EP | disclosed |