Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 15/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288696 | 0.99 | FLT3 (0.73) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8289838 | 0.98 | RAB9A (0.72) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8289498 | 0.86 | FLT3 (0.79) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5455812 | 0.86 | MAPT (0.58) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8288685 | 0.85 | FLT3 (0.77) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8289526 | 0.84 | RAB9A (0.95) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8290663 | 0.83 | FLT3 (1.00) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14366842 | 0.82 | FLT3 (1.00) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8289693 | 0.82 | FLT3 (0.77) | FLT3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5463079 | 0.82 | FLT3 (1.00) | FLT3NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |