Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685696 | 0.88 | ELANE (0.37) | ELANEKMT2A | |
| SCHEMBL8289687 | 0.85 | PSMB9 (0.45) | ELANEPSMB9PSMB8PSMB5 | |
| SCHEMBL13685619 | 0.78 | TERF2 (0.40) | ELANE | |
| SCHEMBL8291442 | 0.75 | CASP3 (0.36) | ELANE | |
| SCHEMBL12607839 | 0.75 | TERF2 (0.36) | ELANEPSMB9PSMB8PSMB5 | |
| SCHEMBL13685755 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL13685770 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL12856044 | 0.74 | CYP3A4 (0.36) | ELANE | |
| SCHEMBL13685129 | 0.73 | BACE1 (0.36) | ELANE | |
| SCHEMBL13686171 | 0.73 | BACE1 (0.36) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |