Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065092 | 0.88 | DPP4 (0.50) | DPP4 | |
| SCHEMBL13139851 | 0.88 | DPP4 (0.50) | DPP4 | |
| SCHEMBL8291759 | 0.82 | DPP4 (0.46) | ALDH1A1KDM4EKMT2AHPGDDPP4 | |
| SCHEMBL5583883 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EKMT2AGAAHPGD | |
| SCHEMBL8291764 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL13139860 | 0.70 | DPP4 (0.56) | DPP4 | |
| SCHEMBL3069484 | 0.70 | DPP4 (0.56) | DPP4 | |
| SCHEMBL13139849 | 0.69 | DPP4 (0.50) | DPP4 | |
| SCHEMBL10832465 | 0.65 | DRD3 (0.54) | ALDH1A1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL5583952 | 0.64 | KDM4E (0.44) | ALDH1A1KDM4EGAAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699777-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2012-12-12 | — | — | EP | disclosed |
| WO-2005026148-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-03-24 | — | — | WO | disclosed |