Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 12/20 | 0.48 |
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742226 | 0.82 | CTSL (0.62) | FFAR2MMEL1MMECTSLCTSB | |
| SCHEMBL1519856 | 0.82 | CTSL (0.62) | FFAR2MMEL1MMECTSLCTSB | |
| SCHEMBL742227 | 0.82 | CTSL (0.62) | FFAR2MMEL1MMECTSLCTSB | |
| SCHEMBL2313273 | 0.78 | FFAR2 (0.77) | FFAR2MMEL1MME | |
| SCHEMBL2313265 | 0.78 | FFAR2 (0.77) | FFAR2MMEL1MME | |
| SCHEMBL22092530 | 0.76 | FFAR2 (0.54) | FFAR2MMEL1MMECTSLCTSV | |
| SCHEMBL14282774 | 0.75 | CTSL (0.59) | FFAR2CTSLCTSBCTSSCTSK | |
| SCHEMBL12752631 | 0.75 | MAPK1 (0.57) | MME | |
| SCHEMBL13702536 | 0.74 | MME (0.59) | FFAR2MMEL1MME | |
| SCHEMBL2319102 | 0.74 | FFAR2 (0.68) | FFAR2MMEL1MMECTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |