Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.73 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.73 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.73 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.73 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954738 | 0.91 | DPP4 (0.74) | DPP4DPP8DPP9DPP7HRH1 | |
| SCHEMBL8290287 | 0.91 | DPP4 (0.74) | DPP4DPP8DPP9DPP7HRH1 | |
| SCHEMBL4952157 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8289172 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14307840 | 0.71 | DPP4 (0.58) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL23752465 | 0.71 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8289096 | 0.71 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8290101 | 0.70 | FFAR2 (0.51) | — | |
| SCHEMBL8288179 | 0.70 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8289103 | 0.70 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |