Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DCK | P27707 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13139852 | 0.88 | DPP4 (0.50) | DPP4 | |
| SCHEMBL3064302 | 0.88 | DPP4 (0.50) | DPP4 | |
| SCHEMBL8290105 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL14238617 | 0.82 | POLB (0.43) | KDM4EALDH1A1HPGDLMNAADORA2A | |
| SCHEMBL5583740 | 0.81 | PIN1 (0.40) | KDM4EALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL8290094 | 0.78 | DPP4 (0.44) | KDM4EALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL8291764 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL13139855 | 0.73 | DPP4 (0.57) | DPP4 | |
| SCHEMBL3075383 | 0.73 | DPP4 (0.57) | DPP4 | |
| SCHEMBL5369275 | 0.67 | NPY5R (0.50) | KDM4EALDH1A1HPGDADORA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699777-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2012-12-12 | — | — | EP | disclosed |
| WO-2005026148-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-03-24 | — | — | WO | disclosed |