⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576430 | 1.00 | — | — | |
| SCHEMBL12081863 | 0.87 | — | — | |
| SCHEMBL8470160 | 0.84 | — | — | |
| SCHEMBL14983858 | 0.81 | TDP1 (0.39) | — | |
| SCHEMBL8160608 | 0.80 | — | — | |
| SCHEMBL5322429 | 0.80 | — | — | |
| SCHEMBL28993340 | 0.80 | — | — | |
| SCHEMBL28299569 | 0.79 | ALDH1A1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28671037 | 0.78 | CACNA2D1 (0.59) | — | |
| SCHEMBL10054693 | 0.76 | CACNA2D1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| US-8420067-B2 | Targeted polylysine dendrimer therapeutic agent | STARPHARMA PTY LTD (AU) | 2013-04-16 | — | — | US | disclosed |
| US-8258259-B2 | Macromolecular compounds having controlled stoichiometry | STARPHARMA PTY LIMITED (AU) | 2012-09-04 | — | — | US | disclosed |
| US-20100292148-A1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | STARPHARMA PTY LTD. (AU) | 2010-11-18 | — | — | US | disclosed |
| US-20100278750-A1 | POLYLYSINE DENDRIMER CONTRAST AGENT | STARPHARMA PTY LTD | 2010-11-04 | — | — | US | disclosed |
| WO-2005032468-A2 | MONOCYCLIC AND BICYCLIC LACTAMS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |