Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 16/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765360 | 0.69 | SMN1; SMN2 (0.41) | ALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL142916 | 0.66 | MEN1 (0.54) | ALDH1A1POLBF10MAPT | |
| SCHEMBL5794492 | 0.66 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL505240 | 0.65 | CA12 (0.53) | POLBF10 | |
| SCHEMBL143175 | 0.65 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2F10MAPT | |
| Hydrochloric Acid SCHEMBL4747459 | 0.64 | CA12 (0.51) | POLBF10 | |
| SCHEMBL1998322 | 0.64 | F10 (0.51) | F10F2 | |
| SCHEMBL6049982 | 0.64 | KMT2A (0.53) | ALDH1A1SMN1; SMN2F10MAPTF2 | |
| SCHEMBL4238560 | 0.64 | F10 (0.58) | POLBF10MAPT | |
| SCHEMBL2645575 | 0.64 | DDB1 (0.41) | ALDH1A1SMN1; SMN2F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005032468-A2 | MONOCYCLIC AND BICYCLIC LACTAMS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |