Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645575 | 0.83 | DDB1 (0.41) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL2539751 | 0.81 | F10 (0.39) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL29348735 | 0.81 | F10 (0.52) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL142916 | 0.81 | MEN1 (0.54) | ALDH1A1MEN1KMT2AMAPTMCL1 | |
| SCHEMBL2531715 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL1277801 | 0.81 | FAAH (0.43) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL92819 | 0.81 | KDM4E (0.57) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL142777 | 0.81 | F10 (0.44) | ALDH1A1KDM4EMGLLF10 | |
| SCHEMBL3561936 | 0.81 | CA12 (0.50) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL4212713 | 0.81 | F10 (0.56) | ALDH1A1ATMMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514348-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | Noetix Pharma LLC (US) | 2025-03-05 | — | — | EP | claimed |
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC | 2024-09-12 | — | — | US | claimed |
| CN-114716365-B | Application of N-substituted phenyl-2-pyridone compound or pharmaceutically acceptable salt thereof in treatment of pulmonary fibrosis | 大连理工大学 | 2024-03-01 | — | — | CN | claimed |
| WO-2023211684-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC (US) | 2023-11-02 | — | — | WO | claimed |
| CN-116655654-A | N-substituted phenyl-2-pyridone endoperoxide and application thereof | 大连理工大学 | 2023-08-29 | — | — | CN | claimed |
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | claimed |
| CN-114716365-A | Application of N-substituted phenyl-2-pyridone compounds or pharmaceutically acceptable salts thereof in treating pulmonary fibrosis | 大连理工大学 | 2022-07-08 | — | — | CN | claimed |
| CN-108883072-A | Granular preparation of 5-methyl-1-phenyl-2- (1H) -pyridone and preparation method thereof | 霍夫曼-拉罗奇有限公司 | 2018-11-23 | — | — | CN | claimed |
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | claimed |
| EP-0866656-B1 | USE OF N-SUBSTITUTED PYRIDONES AS TUMOR NECROSIS FACTOR ALPHA INHIBITORS | MARGOLIN SOLOMON B (US) | 2007-04-25 | — | — | EP | claimed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | claimed |
| EP-1069898-B1 | TOPICAL ANTISEPTIC COMPOSITIONS AND METHODS | MARGOLIN SOLOMON B (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0813409-B1 | TREATMENT OF CYTOKINE GROWTH FACTOR CAUSED DISORDERS | MARGOLIN SOLOMON B (US) | 2004-05-06 | — | — | EP | claimed |
| EP-0702551-B1 | COMPOSITIONS AND METHODS FOR REPARATION AND PREVENTION OF FIBROTIC LESIONS | MARGOLIN SOLOMON B (US) | 2002-09-25 | — | — | EP | claimed |
| US-5962478-A | ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE | INTERMUNE, INC. | 1999-10-05 | — | — | US | claimed |
| US-20260042765-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | AVALYN PHARMA INC (US) | 2025-12-04 | — | — | US | disclosed |
| US-4052509-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4042699-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3974281-A | ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | CHAT, PNPO, PLPBP | ALDH1A1 1343/4885SMN1; SMN2 1338/4885KDM4E 3737/4885 |
| US-20260042765-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | MAP2K2, TTK, MAP2K5 | ALDH1A1 2069/4885SMN1; SMN2 4312/4885KDM4E 212/4885 |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | PNPO, APOB, PLPBP | ALDH1A1 1154/4885SMN1; SMN2 2468/4885KDM4E 1762/4885 |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | PLPBP, PIR, PDXK | ALDH1A1 167/4885SMN1; SMN2 606/4885KDM4E 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.