Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955396 | 0.78 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8290123 | 0.78 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4955293 | 0.70 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ALDH1A1 | |
| SCHEMBL8289007 | 0.70 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ALDH1A1 | |
| SCHEMBL14282750 | 0.67 | DPP4 (0.51) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8290078 | 0.67 | TGFBR1 (0.63) | CTSLCTSBCTSKGBA1MEN1 | |
| SCHEMBL27923093 | 0.64 | GBA1 (0.68) | CTSLCTSBCTSKGBA1MEN1 | |
| SCHEMBL25202837 | 0.64 | ALDH1A1 (0.65) | CTSLCTSBCTSKGBA1MEN1 | |
| SCHEMBL27307114 | 0.64 | NPC1 (0.49) | MEN1KMT2AALDH1A1PKMPOLB | |
| SCHEMBL27917924 | 0.63 | ALDH1A1 (0.70) | CTSLCTSBCTSKGBA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |