Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149789 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10KMT2AKDM4E | |
| SCHEMBL14594880 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL19230394 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL13654279 | 0.77 | HSD17B10 (0.49) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL13654280 | 0.77 | HSD17B10 (0.49) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL7995143 | 0.77 | HSD17B10 (0.49) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL19815496 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL18924944 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL7362051 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPK1BCHELMNAHSD17B10 | |
| SCHEMBL2977220 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK1BCHELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044797-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-05-19 | — | — | WO | disclosed |