Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16470510 | 0.89 | KMT2A (0.70) | ALDH1A1MAPTHSD17B10KDM4ETP53 | |
| SCHEMBL5803763 | 0.83 | MAPT (0.68) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL5803762 | 0.83 | MAPT (0.68) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL5807115 | 0.81 | MAPT (0.71) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL8288726 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| Oxalic Acid SCHEMBL34468543 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL3923517 | 0.78 | KDM4E (0.66) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL34468524 | 0.77 | KMT2A (0.83) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL3913991 | 0.77 | MAPT (0.66) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL8289569 | 0.77 | MAPT (0.59) | ALDH1A1MAPTHSD17B10KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |