Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TLR2 | O60603 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803763 | 0.86 | MAPT (0.68) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL5803762 | 0.86 | MAPT (0.68) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL3923517 | 0.84 | KDM4E (0.66) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL28650118 | 0.83 | TP53 (0.72) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL8289569 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL8290347 | 0.81 | ALDH1A1 (0.69) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL8288726 | 0.80 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL3913991 | 0.80 | MAPT (0.66) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL21247239 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL2949670 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4EHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |