Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.66 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17417196 | 0.83 | MAPT (0.70) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL17417197 | 0.83 | MAPT (0.70) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8290531 | 0.74 | ALDH1A1 (0.68) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL19511930 | 0.74 | LMNA (0.62) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL183203 | 0.73 | ALDH1A1 (1.00) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL14793134 | 0.73 | ALDH1A1 (1.00) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL2574097 | 0.72 | NMT1 (0.69) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL2574096 | 0.72 | NMT1 (0.69) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL196167 | 0.71 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL196166 | 0.71 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2TP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | DNPEP, PREP, ANPEP | MAPT 1400/4885SMN1; SMN2 2829/4885TP53 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.