Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.47 |
| ▸ | CTSG | P08311 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13009387 | 0.85 | MGLL (0.48) | MGLLCTSGKMT2ACAPN1CTSB | |
| SCHEMBL13009097 | 0.82 | MGLL (0.50) | MGLLCTSGKMT2ACMA1L3MBTL1 | |
| SCHEMBL409062 | 0.82 | CMA1 (0.57) | MGLLCTSGCAPN1CTSBCMA1 | |
| SCHEMBL8291221 | 0.77 | MGLL (0.49) | MGLLCTSGKMT2ACAPN1CTSB | |
| SCHEMBL15290587 | 0.77 | MGLL (0.54) | MGLLKMT2ACAPN1CTSBL3MBTL1 | |
| SCHEMBL27668978 | 0.76 | MGLL (0.67) | MGLLKMT2ACAPN1CTSBL3MBTL1 | |
| SCHEMBL14000867 | 0.76 | CTSG (0.49) | MGLLCTSGKMT2ACAPN1CTSB | |
| SCHEMBL8291194 | 0.76 | MGLL (0.55) | MGLLKMT2ACAPN1CTSBL3MBTL1 | |
| SCHEMBL10197956 | 0.75 | MGLL (0.56) | MGLLKMT2ACAPN1CTSBL3MBTL1 | |
| SCHEMBL10317420 | 0.75 | MGLL (0.50) | MGLLCTSGKMT2ACAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005073214-A2 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-11 | — | — | WO | disclosed |