Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583840 | 0.87 | MEN1 (0.49) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8291979 | 0.78 | KDM4E (0.50) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL14584172 | 0.75 | KDM4E (0.47) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8290357 | 0.68 | ALDH1A1 (0.73) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL39978 | 0.63 | MEN1 (0.53) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL31189997 | 0.63 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL1187777 | 0.63 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL288615 | 0.63 | ALDH1A1 (0.55) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL29571295 | 0.63 | ALDH1A1 (0.55) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL2222022 | 0.62 | KDM4E (0.59) | KDM4EMAPTALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |