Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583840 | 0.92 | MEN1 (0.49) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14584172 | 0.86 | KDM4E (0.47) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8291273 | 0.78 | MEN1 (0.49) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8290357 | 0.73 | ALDH1A1 (0.73) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8290675 | 0.72 | ALDH1A1 (0.59) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14680194 | 0.72 | CDC25B (0.62) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14583824 | 0.71 | ESR2 (0.55) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8290359 | 0.70 | MAPT (0.55) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18195806 | 0.66 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14680238 | 0.63 | ESR2 (0.61) | KDM4EMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |