Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291332 | 0.80 | TDP1 (0.35) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL8291368 | 0.75 | MAPT (0.51) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL1065744 | 0.75 | MAPT (0.42) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL8228999 | 0.73 | MAPK1 (0.37) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL3973537 | 0.72 | MAPT (0.69) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL13363663 | 0.71 | GFER (0.46) | MAPTTDP1TSHRALDH1A1RECQL | |
| SCHEMBL8293247 | 0.70 | MAPK1 (0.40) | ARMAPTTDP1TSHRALDH1A1 | |
| SCHEMBL19733666 | 0.70 | CYP3A4 (0.44) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL20788508 | 0.70 | MAPT (0.56) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL2668038 | 0.69 | TSHR (0.49) | MAPTMEN1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |