Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TK2 | O00142 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1469836 | 0.83 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL1469838 | 0.83 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL4977332 | 0.83 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL5983819 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL1172398 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL4283382 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL141407 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL21316784 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL4283383 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL13674189 | 0.82 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608809-B1 | Antiviral tetrahydropyrans | BRISTOL MYERS SQUIBB CO (US) | 1999-07-07 | — | — | EP | claimed |
| EP-0608809-A1 | Antiviral tetrahydropyrans | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0608809-B1 | Antiviral tetrahydropyrans | BRISTOL MYERS SQUIBB CO (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5414096-A | Antiviral tetrahydropyrans | BRISTOL-MYERS SQUIBB CO. (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0608809-A1 | Antiviral tetrahydropyrans | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |
| US-5314893-A | Antiviral tetrahydropyrans | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-24 | — | — | US | disclosed |