Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.50 |
| ▸ | PTPRC | P08575 | 3/20 | 0.50 |
| ▸ | PTPRB | P23467 | 2/20 | 0.50 |
| ▸ | PTPRE | P23469 | 2/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 2/20 | 0.47 |
| ▸ | AIP | O00170 | 1/20 | 0.43 |
| ▸ | SGTA | O43765 | 1/20 | 0.43 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.43 |
| ▸ | STIP1 | P31948 | 1/20 | 0.43 |
| ▸ | PPP5C | P53041 | 1/20 | 0.43 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.43 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189416 | 0.90 | PTPN1 (0.53) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL14438846 | 0.85 | PTPN1 (0.54) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL13026595 | 0.85 | PTPN1 (0.52) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL15259283 | 0.83 | PTPN1 (0.66) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL8293361 | 0.81 | PTPN1 (0.69) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL14704057 | 0.76 | PTPN1 (0.42) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6314541 | 0.75 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL15259280 | 0.75 | PTPN1 (0.41) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL5837972 | 0.68 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL22372483 | 0.65 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005027978-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2005-03-31 | — | — | WO | disclosed |