Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.69 |
| ▸ | AIP | O00170 | 1/20 | 0.60 |
| ▸ | SGTA | O43765 | 1/20 | 0.60 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.60 |
| ▸ | STIP1 | P31948 | 1/20 | 0.60 |
| ▸ | PPP5C | P53041 | 1/20 | 0.60 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.60 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.58 |
| ▸ | PTPRC | P08575 | 3/20 | 0.58 |
| ▸ | PTPRB | P23467 | 2/20 | 0.58 |
| ▸ | PTPRE | P23469 | 2/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.57 |
| ▸ | PTPRA | P18433 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15259283 | 0.88 | PTPN1 (0.66) | PTPN1AIPSGTATOMM70STIP1 | |
| SCHEMBL6314541 | 0.82 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL8292908 | 0.81 | PTPN1 (0.60) | PTPN1AIPSGTATOMM70STIP1 | |
| SCHEMBL13026595 | 0.79 | PTPN1 (0.52) | PTPN1AIPSGTATOMM70STIP1 | |
| SCHEMBL17189283 | 0.78 | ALDH1A1 (0.72) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL14438846 | 0.77 | PTPN1 (0.54) | PTPN1AIPSGTATOMM70STIP1 | |
| SCHEMBL17189416 | 0.76 | PTPN1 (0.53) | PTPN1AIPSGTATOMM70STIP1 | |
| SCHEMBL5451446 | 0.74 | AIP (0.71) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL5453282 | 0.74 | AIP (0.71) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL5837972 | 0.74 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2932981-B1 | Albumin-binding derivatives of GLP-1 | NOVO NORDISK AS (DK) | 2021-06-16 | — | — | EP | disclosed |
| US-20160108102-A1 | Novel GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2016-04-21 | — | — | US | disclosed |
| EP-2932981-A2 | Albumin-binding derivatives of GLP-1 | NOVO NORDISK A/S (DK) | 2015-10-21 | — | — | EP | disclosed |
| US-20130244931-A1 | Novel GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2013-09-19 | — | — | US | disclosed |
| US-20130244931-A1 | Novel GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2013-09-19 | — | — | US | disclosed |
| US-20130053315-A1 | NOVEL GLP-1 DERIVATIVES | NOVO NORDISK A/S | 2013-02-28 | — | — | US | disclosed |
| US-20130053315-A1 | NOVEL GLP-1 DERIVATIVES | NOVO NORDISK A/S | 2013-02-28 | — | — | US | disclosed |
| US-20130040884-A1 | ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG | NOVO NORDISK A/S | 2013-02-14 | — | — | US | disclosed |
| US-20130040884-A1 | ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG | NOVO NORDISK A/S | 2013-02-14 | — | — | US | disclosed |
| US-20100305032-A1 | Novel GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2010-12-02 | — | — | US | disclosed |
| US-20100305032-A1 | Novel GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2010-12-02 | — | — | US | disclosed |
| US-20070203058-A1 | Novel Glp-1 Derivatives | NOVO NORDISK A/S (DK) | 2007-08-30 | — | — | US | disclosed |
| US-20070203058-A1 | Novel Glp-1 Derivatives | NOVO NORDISK A/S (DK) | 2007-08-30 | — | — | US | disclosed |
| WO-2005027978-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040884-A1 | ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG | FABP1, FABP2, FABP4 | PTPN1 3206/4885AIP 1001/4885SGTA 447/4885 |
| US-20130053315-A1 | NOVEL GLP-1 DERIVATIVES | GLP1R, GIPR, IAPP | PTPN1 1612/4885AIP 1000/4885SGTA 208/4885 |
| US-20160108102-A1 | Novel GLP-1 Derivatives | GLP1R, GIPR, IAPP | PTPN1 1612/4885AIP 1000/4885SGTA 208/4885 |
| US-20100305032-A1 | Novel GLP-1 Derivatives | GLP1R, GIPR, IAPP | PTPN1 1612/4885AIP 1000/4885SGTA 208/4885 |
| US-20070203058-A1 | Novel Glp-1 Derivatives | GLP1R, GIPR, NPY4R | PTPN1 258/4885AIP 402/4885SGTA 404/4885 |
| US-20130244931-A1 | Novel GLP-1 Derivatives | GLP1R, GIPR, IAPP | PTPN1 1612/4885AIP 1000/4885SGTA 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.