SCHEMBL14438846

SCHEMBL14438846

COCCOCCNC(=O)CC1CCc2c(sc(NC(=O)C(=O)O)c2C(=O)O)C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 12/20 0.54
▸ PTPN2 P17706 4/20 0.43
▸ PTPRC P08575 3/20 0.43
▸ PTPRB P23467 2/20 0.43
▸ PTPRE P23469 2/20 0.43
▸ PTPN6 P29350 1/20 0.43
▸ PTPRA P18433 2/20 0.41
▸ TNF P01375 3/20 0.41
▸ NOD1 Q9Y239 3/20 0.41
▸ CNR2 P34972 3/20 0.41
▸ CNR1 P21554 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ ALOX12 P18054 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026595 0.93 PTPN1 (0.52) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL17189416 0.91 PTPN1 (0.53) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL8292908 0.85 PTPN1 (0.60) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL14704057 0.83 PTPN1 (0.42) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL8293361 0.77 PTPN1 (0.69) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL6314541 0.72 PTPN1 (1.00) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL5837972 0.63 PTPN1 (1.00) PTPN1PTPN2PTPRCPTPRBPTPRE
SCHEMBL26271467 0.61 EPHX2 (0.39) KDM4EPOLBHSD17B10
SCHEMBL30921001 0.61 ALDH1A1 (0.47) KDM4EALDH1A1MEN1KMT2A
SCHEMBL24397610 0.60 ENO1 (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070203058-A1 Novel Glp-1 Derivatives NOVO NORDISK A/S (DK) 2007-08-30 — — US disclosed
US-20070203058-A1 Novel Glp-1 Derivatives NOVO NORDISK A/S (DK) 2007-08-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203058-A1 Novel Glp-1 Derivatives GLP1R, GIPR, NPY4R PTPN1 258/4885PTPN2 435/4885PTPRC 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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