Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572705 | 0.90 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPK1APOBEC3G | |
| SCHEMBL8292749 | 0.87 | KMT2A (0.48) | KDM4EMEN1KMT2AMAPK1APOBEC3G | |
| SCHEMBL8292747 | 0.81 | HSP90AA1 (0.55) | MEN1KMT2AMAPK1ALDH1A1TSHR | |
| SCHEMBL8297238 | 0.81 | POLB (0.53) | KDM4EMEN1KMT2AMAPK1POLB | |
| SCHEMBL8300446 | 0.80 | MEN1 (0.54) | MEN1KMT2AMAPK1APOBEC3GALOX15 | |
| SCHEMBL8301192 | 0.79 | KMT2A (0.48) | KDM4EMEN1KMT2AMAPK1POLB | |
| SCHEMBL8292897 | 0.77 | HPGD (0.58) | MEN1KMT2AMAPK1APOBEC3GALOX15 | |
| SCHEMBL8570583 | 0.77 | KMT2A (0.44) | KDM4EMEN1KMT2AMAPK1APOBEC3G | |
| SCHEMBL8297964 | 0.77 | SMN1; SMN2 (0.49) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8298680 | 0.76 | HSP90AA1 (0.48) | MEN1KMT2AMAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |