Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292749 | 0.90 | KMT2A (0.48) | KMT2AMAPK1MEN1ALOX15APOBEC3A | |
| SCHEMBL8572705 | 0.88 | KDM4E (0.48) | KMT2AMAPK1MEN1ALOX15APOBEC3A | |
| SCHEMBL8291728 | 0.83 | HPGD (0.49) | KMT2AMEN1POLBTSHRKDM4E | |
| SCHEMBL8291729 | 0.83 | LMNA (0.51) | KMT2AMAPK1POLBTSHRKDM4E | |
| SCHEMBL8292507 | 0.82 | HPGD (0.48) | KMT2AMAPK1POLBTSHRKDM4E | |
| SCHEMBL8574890 | 0.81 | KMT2A (0.47) | KMT2AMAPK1MEN1POLBTSHR | |
| SCHEMBL8566730 | 0.78 | HPGD (0.47) | KMT2AMAPK1POLBTSHRKDM4E | |
| SCHEMBL8293108 | 0.77 | KDM4E (0.47) | KMT2AMAPK1MEN1ALOX15APOBEC3A | |
| SCHEMBL8298215 | 0.77 | MEN1 (0.56) | KMT2AMAPK1MEN1ALOX15APOBEC3A | |
| SCHEMBL8301263 | 0.76 | POLB (0.50) | KMT2AMAPK1POLBTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |