Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910496 | 0.98 | CYP19A1 (0.55) | CYP19A1TRPA1TSHRRECQLCYP11B2 | |
| SCHEMBL4864390 | 0.95 | CYP19A1 (0.57) | CYP19A1TRPA1TSHRRECQLCYP11B2 | |
| SCHEMBL1000330 | 0.91 | CYP19A1 (0.61) | CYP19A1TRPA1CYP11B2 | |
| SCHEMBL17493873 | 0.88 | AAK1 (0.54) | CYP19A1TRPA1TSHRRECQLCYP11B2 | |
| SCHEMBL14174294 | 0.81 | CYP19A1 (0.52) | CYP19A1TRPA1CYP11B2 | |
| SCHEMBL16612734 | 0.81 | CYP19A1 (0.52) | CYP19A1TRPA1CYP11B2 | |
| SCHEMBL2109582 | 0.81 | GBA1 (0.66) | CYP19A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL1550607 | 0.79 | GBA1 (0.63) | CYP19A1CYP11B2 | |
| SCHEMBL16612252 | 0.79 | CYP19A1 (0.56) | CYP19A1CYP11B2 | |
| SCHEMBL28022000 | 0.79 | HRH3 (0.54) | CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848707-B1 | 4-(CYCLOALKYL)PIPERIDINES AND 4-(CYCLOALKYLALKYL)-PIPERIDINES DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1999-08-04 | — | — | EP | disclosed |
| EP-0848707-A1 | 4-(CYCLOALKYL)PIPERIDINES AND 4-(CYCLOALKYLALKYL)-PIPERIDINES DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997009309-A1 | 4-(CYCLOALKYL)PIPERIDINE AND 4-(CYCLOALKYLALKYL)PIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |
| WO-1992000760-A1 | METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |