Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000330 | 0.89 | CYP19A1 (0.61) | CYP19A1CYP11B2LOXL2TRPA1ALDH1A1 | |
| SCHEMBL4864390 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP11B2LOXL2TRPA1 | |
| SCHEMBL8293176 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP11B2TRPA1 | |
| SCHEMBL14174294 | 0.80 | CYP19A1 (0.52) | CYP19A1CYP11B2TRPA1KDM4EALDH1A1 | |
| SCHEMBL4203449 | 0.79 | GBA1 (0.59) | ALDH1A1 | |
| SCHEMBL6160526 | 0.79 | GBA1 (0.59) | ALDH1A1 | |
| SCHEMBL8910496 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP11B2TRPA1 | |
| SCHEMBL40077 | 0.78 | MEN1 (0.44) | LOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29210829 | 0.78 | GBA1 (0.57) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30304790 | 0.78 | GBA1 (0.57) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | CYP19A1 1754/4885CYP11B2 397/4885LOXL2 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.