Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000330 | 0.83 | CYP19A1 (0.61) | CYP19A1CYP11B2 | |
| SCHEMBL5675291 | 0.80 | GBA1 (0.57) | — | |
| SCHEMBL4864390 | 0.79 | CYP19A1 (0.57) | CYP19A1CYP11B2 | |
| SCHEMBL8293176 | 0.79 | CYP19A1 (0.57) | CYP19A1CYP11B2 | |
| SCHEMBL8910496 | 0.78 | CYP19A1 (0.55) | CYP19A1CYP11B2 | |
| SCHEMBL4364820 | 0.77 | ESR2 (0.53) | CYP19A1 | |
| SCHEMBL8008639 | 0.77 | OPRM1 (0.42) | LMNA | |
| SCHEMBL5846563 | 0.77 | EPHX2 (0.42) | — | |
| SCHEMBL6785682 | 0.77 | ALDH1A1 (0.50) | LMNA | |
| Bicarbonate SCHEMBL2854194 | 0.76 | GBA1 (0.52) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |