Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.54 |
| ▸ | CTSK | P43235 | 9/20 | 0.54 |
| ▸ | CTSB | P07858 | 8/20 | 0.54 |
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493886 | 0.85 | CTSK (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL6093063 | 0.84 | CTSL (0.76) | CTSLCTSKCTSBCTSS | |
| SCHEMBL3769248 | 0.80 | CTSL (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7811944 | 0.78 | CTSL (0.76) | CTSLCTSKCTSBCTSS | |
| SCHEMBL8266815 | 0.76 | CTSL (0.57) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457932 | 0.75 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457933 | 0.75 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2156792 | 0.75 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL28457934 | 0.75 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL27663090 | 0.75 | CTSL (0.51) | CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021487-A1 | CATHEPSIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2005-03-10 | — | — | WO | disclosed |